Whilst pottering about with my printer the other day, it occurred to me that I've never seen mention here of using custom paper sizes - I bet most of us are sticking together bits of A4 (I've given up with telex roll for building templates on - too flimsy!)
This may be old hat to some, but it might be worth looking at your printer driver settings to see if you can set a custom paper size. For instance, my new Canon MP499 (an A4 printer) can go up to 420x676mm, but not both dimensions at the same time! In practise, this means I can set a paper size of 210mm x 594mm. A piece of A2 paper is 420x594mm, and when cut in half lengthways gives... ...210x594mm. This is equivalent to two bits of A4 end to end, but you actually gain more than that because you gain the space taken by two margins. It does look a little odd when stacked in the printer - make sure it's supported.
In P4, even quite large formations can now fit on a single sheet of paper, and a B8 turnout in S7 just fits onto one sheet of paper. I say paper, but I actually use 250gsm card - look for "250gsm Silky Smooth Thick White Card" on eBay (no connection to the seller, "activepaper"). This stuff is much cheaper than A2 Bristol Board (if you can actually find it in stock anywhere in that size) but has a shiny surface. This means that the ink smudges quite easily even when printed in draft mode and left for 24hrs, but to solve that I varnished it with a polyurethane varnish which both protects the ink and the paper when liquids start being sloshed all over it in the frenzy of track building!
Anyway, this might give someone food for thought